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In a very recent research, we documented the identification and the characterization of a fresh atypical opioid receptor with exclusive unfavorable regulatory Homes in the direction of opioid peptides.1 Our results showed that ACKR3/CXCR7, hitherto often known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, can be a broad-spectr